<scp>MEF2D</scp> Aggravates Hepatic Ischaemia–Reperfusion Injury by Transcriptionally Regulating <scp>CXCL1</scp> Through Interacting With <scp>NAT10</scp>
NAT10-induced MEF2D acetylation aggravates hepatic IRI by positively regulating transcription of CXCL1 in hepatocytes, which provides a promising therapeutic target for hepatic IRI.
Authors
- Chengbiao Xue
- Qifa Ye (ORCID: https://orcid.org/0000-0002-2797-4804)
- Yan Xiong (ORCID: https://orcid.org/0000-0003-0676-8267)
- Shaojun Ye (ORCID: https://orcid.org/0000-0001-6411-1752)
- Zhongshan Lu (ORCID: https://orcid.org/0000-0003-4634-061X)
- Rui Zhou (ORCID: https://orcid.org/0000-0002-9927-5236)
- Wei Zhou (ORCID: https://orcid.org/0000-0002-0879-5763)
- Liyang Pan
- Zhongzhong Liu (ORCID: https://orcid.org/0000-0002-1415-7784)
- Lihua Zhou
- Zhenxu Deng
- Quanwei Cheng
Institutions
- Central South University (CN)
- Wuhan University (CN)
- Zhongnan Hospital of Wuhan University (CN)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- Liver International
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1111/liv.70315
- Citations
- 1
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China