Outcomes for Patients Aged 12–18 Months With Metastatic <i>MYCN</i> Non‐Amplified Neuroblastoma and Unfavorable Biologic Features (“Mixed Biology Toddlers”): A Report From the International Neuroblastoma Risk Group (INRG) Project
Mixed biology toddlers have lower EFS and OS compared to those whose tumors have favorable biologic features. Inclusion in high-risk NBL trials should be considered for this rare subgroup.
Authors
- Wendy B. London (ORCID: https://orcid.org/0000-0003-3571-6538)
- Julie R. Park (ORCID: https://orcid.org/0000-0002-6777-9165)
- Keri A. Streby (ORCID: https://orcid.org/0000-0002-2469-2553)
- Miki Ohira (ORCID: https://orcid.org/0000-0001-9105-1142)
- Meredith S. Irwin (ORCID: https://orcid.org/0000-0002-2452-5181)
- James R. Anderson (ORCID: https://orcid.org/0000-0003-2441-0728)
- Sara Michele Federico (ORCID: https://orcid.org/0000-0002-5807-4876)
- Pei‐Chi Kao
- Mark A. Applebaum (ORCID: https://orcid.org/0000-0001-9766-8477)
- Carolina Rosswog (ORCID: https://orcid.org/0000-0002-8855-6198)
- Thomas F. Cash (ORCID: https://orcid.org/0000-0002-1128-784X)
- Navin Pinto (ORCID: https://orcid.org/0000-0002-8775-6710)
- Mallory Taylor (ORCID: https://orcid.org/0000-0002-8998-4530)
Institutions
- St. Jude Children's Research Hospital (US)
- Nationwide Children's Hospital (US)
- Harvard University (US)
- Emory University (US)
- University of Toronto (CA)
- University of Washington (US)
- Hospital for Sick Children (CA)
- University of Chicago (US)
- Seattle Children's Hospital (US)
- Aflac (United States) (US)
- Saitama Cancer Center (JP)
- SickKids Foundation (CA)
- Children's Healthcare of Atlanta (US)
- University Hospital Cologne (DE)
- Dana-Farber/Boston Children's Cancer and Blood Disorders Center (US)
- University of Nebraska Medical Center (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- Pediatric Blood & Cancer
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1002/pbc.31968
- Primary Topic
- Neuroblastoma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00