Exploring the mediating role of telomere length in the association between physical activity and bone mineral density

Reduced physical activity and accelerated telomere attrition were related with BMD decline, and TL partially mediated the association. These findings suggest that enhancing physical activity could mitigate telomere shortening and promote bone health.

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Publication Details

Journal
Aging Clinical and Experimental Research
Published
2025-08-29
DOI
https://doi.org/10.1007/s40520-025-03176-4
Primary Topic
Telomeres, Telomerase, and Senescence
Type
article
Field-Weighted Citation Impact
0.00
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article

Exploring the mediating role of telomere length in the association between physical activity and bone mineral density

Xiang Zhao, Yinhui Shi, Mengling Tang
1 links
Aging Clinical and Experimental Research
Telomeres, Telomerase, and Senescence
article

Exploring the mediating role of telomere length in the association between physical activity and bone mineral density

Xiang Zhao, Yinhui Shi, Mengling Tang
article en

Abstract

Reduced physical activity and accelerated telomere attrition were related with BMD decline, and TL partially mediated the association. These findings suggest that enhancing physical activity could mitigate telomere shortening and promote bone health.

Aging Clinical and Experimental ResearchVol. 37(1)
Zhejiang Lab (CN), Blood Center of Zhejiang Province (CN), Second Affiliated Hospital of Zhejiang University (CN), Cixian People's Hospital (CN), Zhejiang University (CN)
Openalex Percentile: Top 71%
Telomeres, Telomerase, and Senescence
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