Comparison of Condylar Remodelling After Mandibular Advancement in Mice With Normal Nasal Breathing and Unilateral Nasal Obstruction
The increase in condylar bone formation in the UNO + MA group was significantly higher than that in the NNB + MA group. Mechanistically, the MA under UNO condition thickens the condylar cartilage layer and facilitates the upregulation of HIF-1α expression in the condylar subchondral bone, thereby promoting the coupling between H-type angiogenesis and osteogenesis.
Authors
- Hegang Li (ORCID: https://orcid.org/0000-0002-2029-4064)
- Yun Hu (ORCID: https://orcid.org/0000-0003-0501-4009)
Institutions
- Guangdong Province Stomatological Hospital (CN)
- Stomatology Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Journal of Oral Rehabilitation
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1111/joor.70052
- Primary Topic
- Craniofacial Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China