The dual role of taurine in cancer and immune metabolism
Taurine is a conditionally essential amino acid with paradoxical roles in cancer, as both tumor and immune cells rely on it for vital functions. Here, we discuss the emerging context-dependent functions of taurine and propose therapeutic strategies that leverage or inhibit its metabolism to modulate cancer progression and immunity.
Authors
- Miaochun Xu (ORCID: https://orcid.org/0000-0002-9023-1755)
- Canhui Cao (ORCID: https://orcid.org/0000-0002-7328-0264)
- Yu Yang (ORCID: https://orcid.org/0000-0001-9173-316X)
Institutions
- Peking University (CN)
- Peking University Third Hospital (CN)
- Tongji Hospital (CN)
- Union Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Trends in Endocrinology and Metabolism
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1016/j.tem.2025.08.001
- Citations
- 4
- Primary Topic
- Aldose Reductase and Taurine
- Type
- article
- Field-Weighted Citation Impact
- 4.61
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hubei Province
- Tongji University