Whole genome transcriptional analysis of intestinal biopsies and blood cells indicate genes involved in antioxidant defense systems, amino acid metabolism and antigen presentation in the pathogenesis of celiac disease
Differentially expressed genes in cases and controls indicate crosstalk between molecular pathways involved in antioxidant defense, immune regulation, and nutrient signaling in the pathogenesis of celiac disease.
Authors
- Daniel Agardh (ORCID: https://orcid.org/0000-0003-1435-1234)
- Sanna Abrahamsson (ORCID: https://orcid.org/0000-0003-4518-8396)
- Henrik Arnell (ORCID: https://orcid.org/0000-0001-5012-8203)
- Åsa Torinsson Naluai (ORCID: https://orcid.org/0000-0002-0504-6492)
- Audur H. Gudjónsdóttir
- Shafir Sabbag
Institutions
- Karolinska University Hospital (SE)
- Lund University (SE)
- Sahlgrenska University Hospital (SE)
- Karolinska Institutet (SE)
- University of Gothenburg (SE)
Publication Details
- Journal
- BMC Medicine
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1186/s12916-025-04261-1
- Citations
- 3
- Primary Topic
- Celiac Disease Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 5.43
Funders
- Svenska Forskningsrådet Formas
- Knut och Alice Wallenbergs Stiftelse
- Vetenskapsrådet
- Göteborgs Universitet
- Science for Life Laboratory