Integrative single-cell and bulk transcriptomic analysis reveals the landscape of T cell mitotic catastrophe associated genes in esophageal squamous cell carcinoma
The prognostic model based on MCAGs we developed serves as an effective tool for predicting outcomes in ESCC.T cell-specific MCAGs drive intratumoral heterogeneity in ESCC, serving as potential prognostic biomarkers and therapeutic targets.
Authors
- Tao Zheng (ORCID: https://orcid.org/0000-0002-8073-4455)
- Shuang Li (ORCID: https://orcid.org/0000-0003-3929-2752)
- Haitao Ma (ORCID: https://orcid.org/0000-0002-9107-2928)
- Nan Wang
- Yazhou Liu (ORCID: https://orcid.org/0000-0002-0135-210X)
- Kai Xie
Institutions
- Wannan Medical College (CN)
- Jiangsu University (CN)
- Soochow University (CN)
- Affiliated Hospital of Jiangsu University (CN)
Publication Details
- Journal
- Human Genomics
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1186/s40246-025-00815-9
- Citations
- 1
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.81