Kurarinone protects against renal injury and fibrosis after unilateral ureteral obstruction through enhancement of the Nrf-2 signaling pathway
KAR inhibited renal fibrosis and inflammation through the Keap1/Nrf-2 pathway, indicating that it may become a small molecular drug for chronic kidney disease.
Authors
- Qian Yang (ORCID: https://orcid.org/0000-0001-5906-6221)
- Tiancao Dong (ORCID: https://orcid.org/0000-0001-7805-4154)
- Xiandong Liu
- Tong Liu (ORCID: https://orcid.org/0000-0001-9234-1328)
- Chunxue Wang (ORCID: https://orcid.org/0000-0003-3154-0985)
- Dongyang Zhao (ORCID: https://orcid.org/0000-0003-1926-2708)
- Sen Jiang (ORCID: https://orcid.org/0009-0000-1832-1513)
- Yi Gu
Institutions
- Tongji University (CN)
- Shanghai East Hospital (CN)
Publication Details
- Journal
- Journal of Molecular Histology
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1007/s10735-025-10578-1
- Primary Topic
- Moringa oleifera research and applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00