Pediatric pulmonary arterial hypertension: global epidemiology and disease burden during the period 1990 to 2021

Globally, prevalence, mortality, and DALYs of pediatric PAH show a declining trend from 1990 to 2021. Females exhibited higher incidence and prevalence rate but lower mortality and DALYs. 10-14 years had the highest prevalence, whereas high PAH-related mortality in neonates remains a critical concern. Tailored health policies for PAH management are needed.

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Publication Details

Journal
Frontiers in Cardiovascular Medicine
Published
2025-08-29
DOI
https://doi.org/10.3389/fcvm.2025.1544545
Primary Topic
Pulmonary Hypertension Research and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Pediatric pulmonary arterial hypertension: global epidemiology and disease burden during the period 1990 to 2021

Chenghong Li, Fajiu Li, Rongguo Zhang, Zhongmei Wen et al.
Frontiers in Cardiovascular Medicine
Pulmonary Hypertension Research and Treatments
article

Pediatric pulmonary arterial hypertension: global epidemiology and disease burden during the period 1990 to 2021

Chenghong Li, Fajiu Li, Rongguo Zhang, Zhongmei Wen, Ying Chen, Xiaobei Wang, Yongxiao Zheng
article en

Abstract

Globally, prevalence, mortality, and DALYs of pediatric PAH show a declining trend from 1990 to 2021. Females exhibited higher incidence and prevalence rate but lower mortality and DALYs. 10-14 years had the highest prevalence, whereas high PAH-related mortality in neonates remains a critical concern. Tailored health policies for PAH management are needed.

Frontiers in Cardiovascular MedicineVol. 12
Shandong University (CN), Jilin University (CN), First Hospital of Jilin University (CN), Wuhan Sixth Hospital (CN)
Natural Science Foundation of Hubei Province
Openalex Percentile: Top 67%
Pulmonary Hypertension Research and Treatments
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