User experience and hemostatic efficacy: Comparative analysis of commercial agents in junctional and hepatic hemorrhage models
All 5 hemostatic agents showed similar efficacy in controlling junctional and intra-abdominal hemorrhage, with no significant differences in hemostasis, rebleed rate, or survival by experience level. However, more ChitoSAM applications were needed for junctional hemorrhage control in the absence of experience. All tested dressings show promise for rapid hemorrhage control.
Authors
- J. T. Green (ORCID: https://orcid.org/0000-0001-5947-9464)
- Brandon W. Propper
- Matthew J. Bradley (ORCID: https://orcid.org/0000-0002-0375-3855)
- Justin Hutzler
- Woo S. (ORCID: https://orcid.org/0000-0002-9641-9505)
- John Mares
- Jason S. Radowsky (ORCID: https://orcid.org/0000-0002-0316-9907)
- Patrick F. Walker (ORCID: https://orcid.org/0000-0002-0871-2702)
- Lauren M. Heyda
- David M. Burmeister (ORCID: https://orcid.org/0000-0002-1256-0158)
- Adelle M. Dagher
- Kyle Patterson
- Meredith Lackie
- Zain Baig
Institutions
- Uniformed Services University of the Health Sciences (US)
- Walter Reed National Military Medical Center (US)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1371/journal.pone.0330696
- Primary Topic
- Hemostasis and retained surgical items
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Army Medical Research and Development Command