The use of a combination of amino acids (arginine, betaine, and carnitine) and riboflavin in pediatric practice (review article)

Aim - to analyze the literature data on the role of amino acids, in particular arginine, betaine and carnitine in pediatric practice. Information was searched in the Web of Science, Scopus, PubMed Central, Google Scholar databases using the following keywords: amino acids, arginine, betaine, carnitine, riboflavin, children. Amino acids are involved in many metabolic processes, in particular in the production of hormones, neurotransmitters and enzymes, contribute to the synthesis of nucleotides, maintenance of redox balance, cell and organism function. According to the literature, they play a fundamental role in childhood in building tissues, supporting brain development, participating in the synthesis of neurotransmitters, which is important for cognitive development, attention, and memory, supporting the immune system and the body's ability to recover from stress, injuries, and physical exertion. In addition to their physiological functions, amino acids are also active therapeutic ingredients used in the prevention and treatment of various diseases, including those of the nervous, cardiovascular, digestive, immune and endocrine systems. Arginine can help improve blood flow to organs that are stressed during intoxication, such as the liver and kidneys, and stimulate metabolism and the elimination of toxins. Carnitine can help maintain the body's energy balance by promoting the use of fatty acids as an energy source, which helps the body recover after intoxication. Betaine can help improve detoxification, support liver function, and reduce toxic substances in the body. Riboflavin, due to its antioxidant properties, can reduce cell damage caused by free radicals that occur during intoxication. Conclusions. The combination of the amino acids arginine, betaine, carnitine and the addition of riboflavin can be extremely useful in pediatrics, since each of these components has specific properties that can complement each other, providing comprehensive support for children's health. The authors declare no conflict of interest.