Application of combined multiple organ resection in the treatment of locally advanced gastric cancer

This study analyzes the application value of extended multi-organ resection in the treatment of locally advanced gastric cancer, and to provide reference for the clinical diagnosis and treatment of locally advanced gastric cancer patients. From January 2016 to April 2022, 64 cases of locally advanced gastric cancer admitted to our hospital were analyzed retrospectively. Combined multiple organ resection was used as the treatment strategy, and the general information and surgical data of patients were analyzed to evaluate the prognosis of extended multi-organ resection in the treatment of locally advanced gastric cancer and the factors affecting these clinical outcomes. A total of 64 patients with locally advanced gastric cancer were included, including 34 males and 30 females, with an average age of 57.28 ± 12.27 years. Among them, combined pancreatectomy was performed in 25 cases, splenectomy in 20 cases, hepatectomy in 12 cases, pancreaticoduodenectomy in 5 cases, pancreaticoduodenectomy and right colon resection in 1 case, and colon resection in 1 case. The average operation time was 159.64 ± 25.19 minutes and the median intraoperative bleeding was 150 mL. All 64 patients achieved R0 resection, and all patients were followed up. Postoperative complications occurred in 18 cases, of which the mortality rate was 16.67% (3/18). The 1-year, 3-year, and 5-year survival rates were 59.4%, 35.9%, and 14.6%, respectively. It is feasible to treat locally advanced gastric cancer by extended combined organ resection. As long as the indications are strictly grasped, the overall prognosis of patients can be improved.