Imatinib For Treatment of Multifocal Maxillofacial Giant Cell Lesions: A Case Series

Maxillofacial giant cell lesions (MGCLs) can lead to disfigurement and functional impairments. Management often involves a combination of operative and nonoperative strategies. This case series presents the first reported use of imatinib for multifocal MGCLs in a patient with Noonan syndrome, alongside 2 patients with cherubism.

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Journal
Journal of Pediatric Hematology/Oncology
Published
2025-08-28
DOI
https://doi.org/10.1097/mph.0000000000003087
Primary Topic
Histiocytic Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Imatinib For Treatment of Multifocal Maxillofacial Giant Cell Lesions: A Case Series

Sarah Ehling, Aparna Bhat, Kevin G. Gard, Mark A. Egbert et al.
Journal of Pediatric Hematology/Oncology
Histiocytic Disorders and Treatments
article

Imatinib For Treatment of Multifocal Maxillofacial Giant Cell Lesions: A Case Series

Sarah Ehling, Aparna Bhat, Kevin G. Gard, Mark A. Egbert, Jesse T. Han, Tyler Garrett Ketterl
article en

Abstract

Maxillofacial giant cell lesions (MGCLs) can lead to disfigurement and functional impairments. Management often involves a combination of operative and nonoperative strategies. This case series presents the first reported use of imatinib for multifocal MGCLs in a patient with Noonan syndrome, alongside 2 patients with cherubism.

Journal of Pediatric Hematology/OncologyVol. 47(8)
Seattle Children's Hospital (US), University of Washington (US), Seattle Children's Hospital (US), Center for Cancer and Blood Disorders (US), National Medical Research Center of Dentistry and Maxillofacial Surgery (RU)
Openalex Percentile: Top 71%
Histiocytic Disorders and Treatments
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Imatinib For Treatment of Multifocal Maxillofacial Giant Cell Lesions: A Case Series — Sarah Ehling, Aparna Bhat, et al. · Journal of Pediatric Hematology/Oncology (2025) | TGRS Research Map | TGRS