Epigenetic Aging in Childhood Cancer Survivors
Childhood cancer survivors demonstrate increased epigenetic age compared with their healthy siblings. Exposure to radiation was associated with further increased epigenetic age. Epigenetic modulation through DNA methylation may be a potential mechanism contributing to the aging process in childhood cancer survivors.
Authors
- Kathy Dotson
- Beth Speckhart
- Yanzhi Wang (ORCID: https://orcid.org/0000-0002-7025-2751)
- Brinda Mehta
- Prerna Kumar (ORCID: https://orcid.org/0009-0004-5688-8229)
- Susan Gaitros
Institutions
- Illinois College (US)
- Peoria campus of the University of Illinois System (US)
- Children's Hospital of Illinois (US)
Publication Details
- Journal
- Journal of Pediatric Hematology/Oncology
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1097/mph.0000000000003104
- Primary Topic
- Childhood Cancer Survivors' Quality of Life
- Type
- article
- Field-Weighted Citation Impact
- 0.00