High-Resolution aCGH Analysis of the Jurkat Cell Line: Copy Number Alterations and Their Association With Cancer Hallmarks

These findings suggest that Jurkat cells may serve as a valuable model for identifying new targets for cancer research. Further studies are required to confirm the phenotypic implications of these variants, which may open new avenues for exploring the functional impact of these alterations and their potential role in the development of therapies.

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Publication Details

Journal
Cancer Genomics & Proteomics
Published
2025-08-29
DOI
https://doi.org/10.21873/cgp.20539
Primary Topic
Cancer Genomics and Diagnostics
Type
article
Field-Weighted Citation Impact
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article

High-Resolution aCGH Analysis of the Jurkat Cell Line: Copy Number Alterations and Their Association With Cancer Hallmarks

Maria Elisabete Amaral de Moraes, Lucas Eduardo Botelho de Souza, Caroline Aquino Moreira-Nunes, Wallax Augusto Silva Ferreira et al.
Cancer Genomics & Proteomics
Cancer Genomics and Diagnostics
article

High-Resolution aCGH Analysis of the Jurkat Cell Line: Copy Number Alterations and Their Association With Cancer Hallmarks

Maria Elisabete Amaral de Moraes, Lucas Eduardo Botelho de Souza, Caroline Aquino Moreira-Nunes, Wallax Augusto Silva Ferreira, Edivaldo Herculano Corrêa de Oliveira, Luís Costa, André Salim Khayat, Carolina Koury Nassar Amorim, Caio Bezerra Machado, Arthur Berg, MANOEL ODORICO DE MORAES FILHO
article en

Abstract

These findings suggest that Jurkat cells may serve as a valuable model for identifying new targets for cancer research. Further studies are required to confirm the phenotypic implications of these variants, which may open new avenues for exploring the functional impact of these alterations and their potential role in the development of therapies.

Cancer Genomics & ProteomicsVol. 22(5)
Instituto Evandro Chagas (BR), Universidade Federal do Pará (BR)
Gender equality
Openalex Percentile: Top 72%
Cancer Genomics and Diagnostics
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High-Resolution aCGH Analysis of the Jurkat Cell Line: Copy Number Alterations and Their Association With Cancer Hallmarks — Maria Elisabete Amaral de Moraes, Lucas Eduardo Botelho de Souza, et al. · Cancer Genomics & Proteomics (2025) | TGRS Research Map | TGRS