Gene Expression Insights into Cytarabine Resistance in Acute Myeloid Leukemia: The Role of Cytokines

This study identified key genes involved in cytokine dysregulation in cytarabine-resistant HL60 cells, providing potential targets for overcoming drug resistance in AML. These findings offer new avenues for the development of more effective therapies for relapsed or refractory AML patients.

Authors

Institutions

Publication Details

Journal
Cancer Genomics & Proteomics
Published
2025-08-29
DOI
https://doi.org/10.21873/cgp.20533
Primary Topic
Acute Myeloid Leukemia Research
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Gene Expression Insights into Cytarabine Resistance in Acute Myeloid Leukemia: The Role of Cytokines

Chien‐Ho Lee, Tzong‐Ming Shieh, Chung-Yu Yeh, I‐Chen Chen et al.
Cancer Genomics & Proteomics
Acute Myeloid Leukemia Research
article

Gene Expression Insights into Cytarabine Resistance in Acute Myeloid Leukemia: The Role of Cytokines

Chien‐Ho Lee, Tzong‐Ming Shieh, Chung-Yu Yeh, I‐Chen Chen, Yu‐Hsin Tseng, Yin‐Hwa Shih
article en

Abstract

This study identified key genes involved in cytokine dysregulation in cytarabine-resistant HL60 cells, providing potential targets for overcoming drug resistance in AML. These findings offer new avenues for the development of more effective therapies for relapsed or refractory AML patients.

Cancer Genomics & ProteomicsVol. 22(5)
Asia University (TW), China Medical University (TW)
Kaohsiung Medical University, Kaohsiung Medical University Chung-Ho Memorial Hospital
Openalex Percentile: Top 70%
Acute Myeloid Leukemia Research
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.