Programmatically Efficient Separation of Immune Infiltrate and Tumor Gene Expression Overlap Potentials in a Big Data Setting: FASLG Gene Expression-related Survival Distinctions
This study indicates that FASLG CN increases could represent a mechanism of tumor escape from TILs and a prognostic indicator; and tumor FASLG may be a suitable drug target for reducing tumor evasion of T-cells.
Authors
- George Blanck (ORCID: https://orcid.org/0000-0003-1664-0996)
- Mallika Varkhedi
- Toriana R. Dabkowski
- Elizabeth J. Fletcher
Institutions
- University of South Florida (US)
- Moffitt Cancer Center (US)
Publication Details
- Journal
- Cancer Genomics & Proteomics
- Published
- 2025-08-29
- DOI
- https://doi.org/10.21873/cgp.20531
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00