Efficacy of biomarkers in the endochondral phase of fracture repair and healing in long bones: A clinical observational studys
This rigorous data set supports the future prospective use of the CXM biomarker collected by finger prick in interventional fracture studies and/or in observational studies requiring quantitative assessments of long-bone healing.
Authors
- William A. Horton (ORCID: https://orcid.org/0000-0002-5742-7377)
- Justin E. Hellwinkel (ORCID: https://orcid.org/0000-0002-3421-5363)
- Lauren A. Pierpoint (ORCID: https://orcid.org/0000-0002-8540-0534)
- Lucas S. Marchand (ORCID: https://orcid.org/0000-0002-4499-6669)
- Anna Laura Nelson (ORCID: https://orcid.org/0000-0002-1367-6232)
- Graham J. DeKeyser (ORCID: https://orcid.org/0000-0001-9670-8211)
- Nathan N. O’Hara (ORCID: https://orcid.org/0000-0003-0537-3474)
- Kelsey M. O’Hara (ORCID: https://orcid.org/0009-0001-8985-8171)
- Darin Friess (ORCID: https://orcid.org/0000-0002-0534-879X)
- Sheila Sprague (ORCID: https://orcid.org/0000-0003-1466-8063)
- Chelsea S. Bahney (ORCID: https://orcid.org/0000-0001-9808-8888)
- Zachary M. Working (ORCID: https://orcid.org/0000-0003-1768-1001)
- Kaitlyn E. Whitney (ORCID: https://orcid.org/0000-0003-3935-8803)
- Gerard P. Slobogean (ORCID: https://orcid.org/0000-0002-9111-9239)
- Brian Johnstone (ORCID: https://orcid.org/0000-0001-7786-2870)
- Karalynn Lancaster
- Molly Czachor (ORCID: https://orcid.org/0009-0003-3303-9649)
- Theodore Miclau (ORCID: https://orcid.org/0000-0001-7518-7293)
- Sofia Bzovskys
Institutions
- University of Maryland, Baltimore (US)
- Oregon Health & Science University (US)
- University of California, San Francisco (US)
- University of Utah (US)
- Shriners Hospitals for Children - Portland (US)
- Steadman Philippon Research Institute (US)
- McMaster University (CA)
Publication Details
- Journal
- PLoS Medicine
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1371/journal.pmed.1004640
- Citations
- 3
- Primary Topic
- Bone fractures and treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.06
Funders
- Orthopaedic Research and Education Foundation
- AO North America
- Osiris Therapeutics
- Colorado State University
- California Institute of Regenerative Medicine
- Steadman Philippon Research Institute
- Osteosynthesis and Trauma Care Foundation
- McMaster University
- Université de Sherbrooke
- Orthopaedic Trauma Association
- Orthopedic Research and Education Foundation
- AO Foundation
- Geistlich Pharma
- National Institutes of Health