Transorbital ultrasonography reveals persistent decrease in retinal artery flow and optic nerve diameter in treated giant cell arteritis
Utilizing TOS, we demonstrated progressive decrease in retinal artery flow and OND, indicating ongoing impairment in retinal vascular supply and potential optic nerve atrophy despite clinical improvement post-treatment. Our findings suggest that intracranial vascular changes in GCA may respond less effectively to treatment than extracranial vessels and support a shared pathophysiological mechanism in GCA.
Authors
- Valentin Sebastian Schäfer (ORCID: https://orcid.org/0000-0002-6591-5936)
- Pantelis Karakostas (ORCID: https://orcid.org/0000-0001-8421-2745)
- Frank Gerhard Holz (ORCID: https://orcid.org/0000-0001-8019-9272)
- Lara C Burg (ORCID: https://orcid.org/0000-0002-5379-9149)
- Simon Michael Petzinna (ORCID: https://orcid.org/0000-0002-4686-1143)
- Charlotte Behning (ORCID: https://orcid.org/0000-0002-9310-3804)
- Jan Henrik Terheyden (ORCID: https://orcid.org/0000-0002-0174-4066)
- C. Bauer (ORCID: https://orcid.org/0000-0003-3152-6550)
- Robert Patrick Finger (ORCID: https://orcid.org/0000-0003-4253-7597)
Institutions
- Zimmer Biomet (Netherlands) (NL)
- University Hospital Bonn (DE)
- Institut für Medizinische Biometrie, Informatik und Epidemiologie (DE)
- Zimmer Biomet (Germany) (DE)
Publication Details
- Journal
- Lara D. Veeken
- Published
- 2025-08-27
- DOI
- https://doi.org/10.1093/rheumatology/keaf456
- Citations
- 2
- Primary Topic
- Vasculitis and related conditions
- Type
- article
- Field-Weighted Citation Impact
- 3.04