Staggered use of sodium nitroprusside and levosimendan in a patient with refractory cardiogenic shock: a case report

Given the heterogeneous nature of CS and the various physiological derangements, several vasoactive medications may be attempted to try to stabilize or reverse the haemodynamic picture with or without the installation of MCS. These devices have evolved as novel treatment strategies to restore systemic perfusion to allow cardiac recovery in the short-term. But, this case demonstrates the potential of combining vasodilator and inotropic therapies-specifically dobutamine and milrinone with sodium nitroprusside and levosimendan-as a bridge strategy in severe CS when MCS is not feasible.

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Publication Details

Journal
European Heart Journal - Case Reports
Published
2025-08-29
DOI
https://doi.org/10.1093/ehjcr/ytaf430
Primary Topic
Cardiac Arrest and Resuscitation
Type
article
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article

Staggered use of sodium nitroprusside and levosimendan in a patient with refractory cardiogenic shock: a case report

Yasmin de Souza Lima Bitar, André Rodrigues Durães, Joana Madureira Lima, Guilherme José Pimentel Lopes de Oliveira et al.
European Heart Journal - Case Reports
Cardiac Arrest and Resuscitation
article

Staggered use of sodium nitroprusside and levosimendan in a patient with refractory cardiogenic shock: a case report

Yasmin de Souza Lima Bitar, André Rodrigues Durães, Joana Madureira Lima, Guilherme José Pimentel Lopes de Oliveira, L. Franklin
article en

Abstract

Given the heterogeneous nature of CS and the various physiological derangements, several vasoactive medications may be attempted to try to stabilize or reverse the haemodynamic picture with or without the installation of MCS. These devices have evolved as novel treatment strategies to restore systemic perfusion to allow cardiac recovery in the short-term. But, this case demonstrates the potential of combining vasodilator and inotropic therapies-specifically dobutamine and milrinone with sodium nitroprusside and levosimendan-as a bridge strategy in severe CS when MCS is not feasible.

European Heart Journal - Case ReportsVol. 9(9)
Engie (United States) (US), Complexo Hospitalar Universitário Professor Edgard Santos (BR), Hospital de Magalhães Lemos (PT)
Good health and well-being
Openalex Percentile: Top 66%
Cardiac Arrest and Resuscitation
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