Comparative evaluation of β-glucan functional dressing and interferon-α2a plug for vaginal microecology restoration and HPV clearance in women with bacterial vaginosis or aerobic vaginitis

Both β-glucan and IFN-α2a dressings were safe and showed clinical benefits in women with BV or AV and HR-HPV infection. However, β-glucan demonstrated superior outcomes in restoring vaginal microecology and enhancing HPV clearance. These findings suggest that β-glucan may serve as a more effective intravaginal immunomodulatory therapy. Further multicenter studies with larger samples are needed to confirm these results.