Synthesis, crystal structure, anticancer activity and computational studies of novel Pyrazolo[4‘,3’:5,6]pyrano[2,3- <i>d</i> ]pyrimidine derivatives as potential anticancer agents
The synthesized pyrazolopyranopyrimidine derivatives, particularly <b>7</b> and <b>8</b>, show promise as anticancer agents and warrant further investigation.
Authors
- Ali Oubella
- Imane Yamari (ORCID: https://orcid.org/0000-0002-8406-8533)
- Younesse Ait Elmachkouri (ORCID: https://orcid.org/0000-0002-0685-8011)
- Ezaddine Irrou (ORCID: https://orcid.org/0009-0004-7720-4244)
- Samir Chtita (ORCID: https://orcid.org/0000-0003-2344-5101)
- Nada Kheira Sebbar (ORCID: https://orcid.org/0000-0003-4944-1010)
- Yahya Toubi (ORCID: https://orcid.org/0009-0006-8301-4361)
- Joel T. Mague (ORCID: https://orcid.org/0000-0003-3488-1945)
- Mohamed F. Alajmi (ORCID: https://orcid.org/0000-0002-3044-1267)
- Mohamed Labd Taha
Institutions
- Tulane University (US)
- King Saud University (SA)
- Université Ibn Zohr (MA)
- University of Hassan II Casablanca (MA)
Publication Details
- Journal
- Future Medicinal Chemistry
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1080/17568919.2025.2552641
- Citations
- 1
- Primary Topic
- Synthesis and biological activity
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Tulane University