Deep medullary vein dysfunction is associated with cerebral microbleeds in cerebral small vessel disease

DMV dysfunction is positively associated with CMB burden in CSVD, partially mediated by increased extracellular fluid accumulation. These findings suggest that impaired venous drainage and interstitial fluid retention may play a role in the pathogenesis of CMB.

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Publication Details

Journal
Frontiers in Human Neuroscience
Published
2025-08-29
DOI
https://doi.org/10.3389/fnhum.2025.1636248
Primary Topic
Intracerebral and Subarachnoid Hemorrhage Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Deep medullary vein dysfunction is associated with cerebral microbleeds in cerebral small vessel disease

Xinjun Lei, Zhihua Xu, Haiyuan Lan, Jie Yu et al.
Frontiers in Human Neuroscience
Intracerebral and Subarachnoid Hemorrhage Research
article

Deep medullary vein dysfunction is associated with cerebral microbleeds in cerebral small vessel disease

Xinjun Lei, Zhihua Xu, Haiyuan Lan, Jie Yu, Huimei Wang
article en

Abstract

DMV dysfunction is positively associated with CMB burden in CSVD, partially mediated by increased extracellular fluid accumulation. These findings suggest that impaired venous drainage and interstitial fluid retention may play a role in the pathogenesis of CMB.

Frontiers in Human NeuroscienceVol. 19
Lishui University (CN), Tongde Hospital of Zhejiang Province (CN), Lishui Central Hospital (CN), Lishui City People's Hospital (CN)
Openalex Percentile: Top 67%
Intracerebral and Subarachnoid Hemorrhage Research
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