Enhancing vitamin B<sub>5</sub> biosynthesis by multimodule optimization and protein engineering
A multi-module strategy was adopted to construct the de novo synthesis pathway of VB 5 with Escherichia coli as the chassis cells.
Authors
- Yunying Xiao
- Chaoze Liu
- Zhi‐Qiang Liu (ORCID: https://orcid.org/0000-0003-3259-6796)
- Guoping Qian (ORCID: https://orcid.org/0000-0001-9776-9999)
- Junping Zhou (ORCID: https://orcid.org/0000-0001-7355-6032)
- Lidan Zhu
- Xue Cai (ORCID: https://orcid.org/0000-0001-5919-9817)
- Yu‐Guo Zheng (ORCID: https://orcid.org/0000-0002-6358-6243)
- Bo Zhang (ORCID: https://orcid.org/0000-0002-8241-0630)
- Yi Zhu
Institutions
- Wenzhou Medical University (CN)
- State Key Laboratory of Chemical Engineering (CN)
- Dongyang People's Hospital (CN)
- Zhejiang University of Technology (CN)
Publication Details
- Journal
- Green Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5gc02458g
- Citations
- 3
- Primary Topic
- Neurological diseases and metabolism
- Type
- article
- Field-Weighted Citation Impact
- 2.53
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China