A Case of Acute‐Onset <scp>CIDP</scp> With Pleocytosis in Cerebrospinal Fluid Presenting With Recurrent Acute Limb Weakness
ABSTRACT Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an immune‐mediated peripheral neuropathy commonly defined by symmetric involvement of both proximal and distal muscles. This case report describes a rare presentation of acute‐onset CIDP in a 45‐year‐old woman with mixed connective tissue disease and myasthenia gravis. She experienced recurrent episodes of acute limb weakness along with cerebrospinal fluid pleocytosis. Comprehensive electrophysiological studies identified proximal amplitude reductions and temporal dispersion abnormalities, affirming the diagnosis of CIDP. Functional improvement was achieved with appropriate treatment including intravenous immunoglobulin.
Authors
- Hiroyuki Ishiura (ORCID: https://orcid.org/0000-0003-2975-7309)
- Mami Takemoto (ORCID: https://orcid.org/0000-0001-6496-6582)
- Yosuke Osakada (ORCID: https://orcid.org/0000-0002-3354-0463)
- Taijun Yunoki
- Ryuta Morihara (ORCID: https://orcid.org/0000-0002-8912-0994)
- Hisako Tsuji
- Ken Ikegami (ORCID: https://orcid.org/0000-0002-8999-5483)
- Yuki Taira (ORCID: https://orcid.org/0000-0001-6467-5558)
- Toru Yamashita (ORCID: https://orcid.org/0000-0003-3634-5679)
- Akinori Kinoshita
- Yumi Nakada
- Ayumi Uchibori
- Toshikazu Onishi (ORCID: https://orcid.org/0000-0001-7826-3837)
- Chika Matsuoka (ORCID: https://orcid.org/0000-0002-1965-6056)
- Masahiro Ishida (ORCID: https://orcid.org/0009-0003-7497-1053)
- Tomohito Kawano
- Tomoaki Nada
Institutions
- Okayama University (JP)
- Kyorin University (JP)
- Okayama University Hospital (JP)
Publication Details
- Journal
- Neurology and Clinical Neuroscience
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1111/ncn3.70045
- Citations
- 1
- Primary Topic
- Peripheral Neuropathies and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.39