Investigating the effect of Ranolazine drug on the pathophysiology of asthma in a rat model
Ranolazine treatment showed minimal impact on serum IgE levels in asthmatic rats, with a slight reduction that was statistically insignificant. However, Ranolazine treatment resulted in a significant decrease in perivascular and peribronchial inflammation levels compared to the asthmatic group, suggesting a potential therapeutic effect on lung histology changes associated with asthma pathophysiology.
Authors
- Mehdi Koushki (ORCID: https://orcid.org/0000-0003-0071-3505)
- Nasrin Amiri‐Dashatan (ORCID: https://orcid.org/0000-0003-4259-8218)
- Seyyed Shamsadin Athari (ORCID: https://orcid.org/0000-0002-6355-6378)
- Maryam Sadeghi
- Sarina Shahrooz
- Mehdi Aghamohammadi
- Hadi khodabandeloo
Institutions
- Zanjan University of Medical Sciences (IR)
Publication Details
- Journal
- BMC Research Notes
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1186/s13104-025-07455-1
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Zanjan University of Medical Sciences
- University of Zanjan
- Student Research Committee, Tabriz University of Medical Sciences