Long-term primary pharmacotherapy of giant prolactinomas: A comparison of different cabergoline dosages

Dopamine agonists are safe and only required treatment in 2/3 of patients treated with pharmacotherapy as a first-line treatment. Higher doses of cabergoline accelerate prolactin normalisation but do not confer additional benefit in early tumour shrinkage.

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Publication Details

Journal
Journal of Clinical & Translational Endocrinology
Published
2025-08-28
DOI
https://doi.org/10.1016/j.jcte.2025.100418
Primary Topic
Pituitary Gland Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Long-term primary pharmacotherapy of giant prolactinomas: A comparison of different cabergoline dosages

Luís San Román, David Netuka, Dietrich Pavel, Martin Májovský et al.
Journal of Clinical & Translational Endocrinology
Pituitary Gland Disorders and Treatments
article

Long-term primary pharmacotherapy of giant prolactinomas: A comparison of different cabergoline dosages

Luís San Román, David Netuka, Dietrich Pavel, Martin Májovský, Václav Hána, J Jana, Kowara Michał, Vaněčková Manuela, Krausová Adéla, Kosák Mikuláš, Masopust Václav
article en

Abstract

Dopamine agonists are safe and only required treatment in 2/3 of patients treated with pharmacotherapy as a first-line treatment. Higher doses of cabergoline accelerate prolactin normalisation but do not confer additional benefit in early tumour shrinkage.

Journal of Clinical & Translational EndocrinologyVol. 41
Charles University (CZ), Na Homolce Hospital (CZ), Military University Hospital Prague (CZ), General University Hospital in Prague (CZ)
Zero hunger
Openalex Percentile: Top 69%
Pituitary Gland Disorders and Treatments
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Long-term primary pharmacotherapy of giant prolactinomas: A comparison of different cabergoline dosages — Luís San Román, David Netuka, et al. · Journal of Clinical & Translational Endocrinology (2025) | TGRS Research Map | TGRS