IMPLICAÇÕES CUTÂNEAS SOBRE O COLÁGENO TIPO I E III NA MENOPAUSA E O USO FACIAL DE BIOESTIMULADORES DE COLÁGENO INJETÁVEIS PARA AUMENTO DA NEOCOLAGÊNESE

With the increase in female longevity, there is growing concern about healthy aging and, consequently, skin health. Menopause is characterized by systemic and cutaneous changes that affect the structure and function of the dermis. Among these changes, the significant reduction in type I and type III collagen synthesis stands out, as these are the main structural components responsible for skin firmness, elasticity, and resilience. The aim of this study was to analyze the implications of menopause on facial dermal collagen integrity and to evaluate the therapeutic potential of injectable collagen biostimulators in inducing neocollagenesis. An integrative literature review was conducted, including studies published between 2020 and 2025 in PubMed, ScienceDirect, and LILACS. The results showed that biostimulators such as calcium hydroxylapatite, poly-L-lactic acid, and polycaprolactone activate fibroblasts and progressively stimulate collagen synthesis, contributing to extracellular matrix regeneration and improved skin quality in menopausal women. In conclusion, these agents represent an effective and safe approach to treating dermal degradation and are essential for developing individualized protocols based on clinical evidence.