Sudden cardiac death in newly diagnosed non-ischaemic or ischaemic cardiomyopathy assessed with a wearable cardioverter-defibrillator: the German nationwide SCD-PROTECT study
The SCD-PROTECT study highlights a substantial risk of SCA due to VT/VF during the early phase of guideline-recommended medical therapy optimization in patients with newly diagnosed reduced LVEF, regardless of ischaemic or non-ischaemic origin. The WCD provided SCD protection, the LVEF could improve to >35% in the majority of these patients and can therefore serve as risk stratification across both aetiologies.
Authors
- Éloi Marijon (ORCID: https://orcid.org/0000-0001-7227-3428)
- Uwe Siebert (ORCID: https://orcid.org/0000-0001-6425-7671)
- Norbert Frey (ORCID: https://orcid.org/0000-0001-7611-378X)
- Johann Bauersachs (ORCID: https://orcid.org/0000-0002-9341-117X)
- Olivier Piot (ORCID: https://orcid.org/0000-0002-6311-4983)
- Marco Metra (ORCID: https://orcid.org/0000-0001-6691-8568)
- Marat Fudim (ORCID: https://orcid.org/0000-0002-8671-7007)
- David Duncker (ORCID: https://orcid.org/0000-0003-2996-6338)
- Lars Siegfried Maier (ORCID: https://orcid.org/0000-0001-9915-4429)
Institutions
- Harvard University (US)
- Inserm (FR)
- Duke University (US)
- Université Paris Cité (FR)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- University Hospital Regensburg (DE)
- Medizinische Hochschule Hannover (DE)
- Massachusetts General Hospital (US)
- Clinical Research Institute (US)
- Hôpital Européen Georges-Pompidou (FR)
- Surgical Specialties (Canada) (CA)
- UMIT - Private Universität für Gesundheitswissenschaften, Medizinische Informatik und Technik (AT)
- Paris Cardiovascular Research Center (FR)
- European Hospital (IT)
- Duke University Hospital (US)
- Centre Cardiologique du Nord (FR)
- University of Brescia (IT)
Publication Details
- Journal
- European Heart Journal
- Published
- 2025-08-17
- DOI
- https://doi.org/10.1093/eurheartj/ehaf668
- Citations
- 8
- Primary Topic
- Cardiac pacing and defibrillation studies
- Type
- article
- Field-Weighted Citation Impact
- 11.11
Funders
- ZOLL Medical Corporation