Severe Hearing Loss in Children With Central Nervous System Tumors: A Population‐Based Cancer in Young People in Canada (CYP‐C) Report

High rates of early HL were observed in children with embryonal tumors. Younger children who received radiotherapy had higher probabilities of early HL, suggesting an additive interaction between age and radiation. Standardized otoprotection and research on cisplatin avoidance and therapy de-escalation in young children with embryonal tumors are urgently needed.

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Publication Details

Journal
Pediatric Blood & Cancer
Published
2025-08-29
DOI
https://doi.org/10.1002/pbc.32024
Primary Topic
Brain Metastases and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Severe Hearing Loss in Children With Central Nervous System Tumors: A Population‐Based Cancer in Young People in Canada (CYP‐C) Report

Juliette Hukin, Samuele Renzi, Hallie Coltin, Craig Erker et al.
Pediatric Blood & Cancer
Brain Metastases and Treatment
article

Severe Hearing Loss in Children With Central Nervous System Tumors: A Population‐Based Cancer in Young People in Canada (CYP‐C) Report

Juliette Hukin, Samuele Renzi, Hallie Coltin, Craig Erker, Paul Craig Nathan, Vijay Ramaswamy, Lucie Lafay‐Cousin, Derek S. Tsang, Annie Huang, Éric Bouffet, Valérie Larouche, Sébastien Perreault, Ofélie Trudeau‐Ferrin, Randy Barber
article en

Abstract

High rates of early HL were observed in children with embryonal tumors. Younger children who received radiotherapy had higher probabilities of early HL, suggesting an additive interaction between age and radiation. Standardized otoprotection and research on cisplatin avoidance and therapy de-escalation in young children with embryonal tumors are urgently needed.

Pediatric Blood & CancerVol. 72(11)
University Health Network (CA), University of British Columbia (CA), University of Toronto (CA), Izaak Walton Killam Health Centre (CA), Hospital for Sick Children (CA), Alberta Children's Hospital (CA), Centre Hospitalier Universitaire Sainte-Justine (CA), Nova Scotia Health Authority (CA), Princess Margaret Cancer Centre (CA), C17 Council (CA), Centre hospitalier universitaire de Québec (CA), Nova Scotia Cancer Centre (CA)
Rally Foundation, Fondation Brain Canada, Public Health Agency of Canada, Australian Government, Cole Foundation, Government of Canada, Pediatric Oncology Group of Ontario, Brain Tumour Foundation of Canada, Public Health Agency, Université de Montréal, Fondation Charles-Bruneau, Fondation De Famille Alvin Segal, Health Canada, Canadian Cancer Society Research Institute, Garron Family Cancer Centre
Openalex Percentile: Top 67%
Brain Metastases and Treatment
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