Adaptive Deep Brain Stimulation Benefits: Younger Patients with Persistent Wearing‐off Symptoms
aDBS shows promise in managing motor symptoms in PD, particularly in patients with pronounced wearing-off and younger patients, by dynamically adjusting stimulation parameters. Although further optimization and long-term studies are necessary, these findings underscore the potential of aDBS to offer personalized treatment options for advanced PD.
Authors
- Naoki Tani (ORCID: https://orcid.org/0000-0003-2169-135X)
- Takahiro Fujinaga (ORCID: https://orcid.org/0009-0001-1754-2063)
- Hui Ming Khoo (ORCID: https://orcid.org/0000-0002-4039-0520)
- Yuya Fujita (ORCID: https://orcid.org/0000-0001-8155-6040)
- Haruhiko Kishima (ORCID: https://orcid.org/0000-0002-9041-2337)
- Satoru Oshino (ORCID: https://orcid.org/0000-0002-4248-2322)
- Nobuhiko Mori (ORCID: https://orcid.org/0000-0001-6537-6322)
- Takuto Emura (ORCID: https://orcid.org/0009-0001-7152-435X)
- Koichi Hosomi (ORCID: https://orcid.org/0000-0001-7731-3302)
- Takahiro Matsuhashi (ORCID: https://orcid.org/0000-0002-8630-478X)
- Yuki Kimoto (ORCID: https://orcid.org/0009-0003-2328-1108)
- Shimpei Miura (ORCID: https://orcid.org/0009-0007-3142-8455)
Institutions
- The University of Osaka (JP)
Publication Details
- Journal
- Movement Disorders Clinical Practice
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1002/mdc3.70311
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00