A Rare Location of Polymorphous Low-Grade Neuroepithelial Tumor of the Young (PLNTY) of the Thalamus: A Case Report and Review of Literature

Polymorphous low-grade neuroepithelial tumor of the young (PLNTY) is a rare CNS WHO Grade I brain tumor that typically affects children and young adults and may be associated with seizures. Thalamic involvement is exceedingly rare. We report a case of a 29-year-old male with persistent paresthesias in the right upper and lower limbs and suspected sensory seizures. Imaging revealed a left thalamic space-occupying lesion. Stereotactic biopsy confirmed PLNTY. The case highlights the rare presentation of PLNTY in an unusual location and in an adult, emphasising the need for accurate pathological diagnosis in atypical presentations.

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Publication Details

Journal
Cureus
Published
2025-08-29
DOI
https://doi.org/10.7759/cureus.91224
Primary Topic
Glioma Diagnosis and Treatment
Type
article
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article

A Rare Location of Polymorphous Low-Grade Neuroepithelial Tumor of the Young (PLNTY) of the Thalamus: A Case Report and Review of Literature

Ashwin Sridhar, Bhaskar Naidu P, Lawrence D'Cruze
Cureus
Glioma Diagnosis and Treatment
article

A Rare Location of Polymorphous Low-Grade Neuroepithelial Tumor of the Young (PLNTY) of the Thalamus: A Case Report and Review of Literature

Ashwin Sridhar, Bhaskar Naidu P, Lawrence D'Cruze
article en

Abstract

Polymorphous low-grade neuroepithelial tumor of the young (PLNTY) is a rare CNS WHO Grade I brain tumor that typically affects children and young adults and may be associated with seizures. Thalamic involvement is exceedingly rare. We report a case of a 29-year-old male with persistent paresthesias in the right upper and lower limbs and suspected sensory seizures. Imaging revealed a left thalamic space-occupying lesion. Stereotactic biopsy confirmed PLNTY. The case highlights the rare presentation of PLNTY in an unusual location and in an adult, emphasising the need for accurate pathological diagnosis in atypical presentations.

CureusVol. 17(8)
Sri Ramachandra Institute of Higher Education and Research (IN)
Openalex Percentile: Top 69%
Glioma Diagnosis and Treatment
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