Newly Diagnosed Celiac Disease in a Patient With a Body Mass Index of 50.8 kg/m<sup>2</sup>

Celiac disease (CD) was previously known to be seen in underweight individuals, with weight loss being one of the key symptoms; however, newer data today is starting to show that most adults with celiac disease are either normal weight, overweight or obese. Here we present a 52-year-old patient with a body mass index (BMI) of 50.8 kg/m<sup>2</sup> who was diagnosed with biopsy-proven CD and her tissue transglutaminase immunoglobulin A level was 45.5 U/mL (0-15 U/mL). CD is becoming increasingly prevalent in overweight and obese individuals, making it essential for clinicians to be aware of this atypical presentation to prevent any delay in diagnosis and improve their quality of life.

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Publication Details

Journal
JGH Open
Published
2025-08-29
DOI
https://doi.org/10.1002/jgh3.70210
Primary Topic
Celiac Disease Research and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Newly Diagnosed Celiac Disease in a Patient With a Body Mass Index of 50.8 kg/m2

Thomas G. Brown, Abdul-Rahman F. Diab, Munish Sachdeva
JGH Open
Celiac Disease Research and Management
article

Newly Diagnosed Celiac Disease in a Patient With a Body Mass Index of 50.8 kg/m2

Thomas G. Brown, Abdul-Rahman F. Diab, Munish Sachdeva
article en

Abstract

Celiac disease (CD) was previously known to be seen in underweight individuals, with weight loss being one of the key symptoms; however, newer data today is starting to show that most adults with celiac disease are either normal weight, overweight or obese. Here we present a 52-year-old patient with a body mass index (BMI) of 50.8 kg/m<sup>2</sup> who was diagnosed with biopsy-proven CD and her tissue transglutaminase immunoglobulin A level was 45.5 U/mL (0-15 U/mL). CD is becoming increasingly prevalent in overweight and obese individuals, making it essential for clinicians to be aware of this atypical presentation to prevent any delay in diagnosis and improve their quality of life.

JGH OpenVol. 9(9)
University of Central Florida (US), College of Central Florida (US), Cardiovascular Institute of Central Florida (US)
Openalex Percentile: Top 66%
Celiac Disease Research and Management
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Newly Diagnosed Celiac Disease in a Patient With a Body Mass Index of 50.8 kg/m<sup>2</sup> — Thomas G. Brown, Abdul-Rahman F. Diab, et al. · JGH Open (2025) | TGRS Research Map | TGRS