Efficacy and safety of a reduced starting dose of cabozantinib (20 mg) plus nivolumab for renal cell carcinoma in real-world practice

A 20-mg starting dose of cabozantinib in C + N therapy can achieve almost the same efficacy as a normal starting dose for patients who are hesitant to start treatment at the normal 40-mg dose.

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Publication Details

Journal
Japanese Journal of Clinical Oncology
Published
2025-08-11
DOI
https://doi.org/10.1093/jjco/hyaf135
Primary Topic
Renal cell carcinoma treatment
Type
article
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article

Efficacy and safety of a reduced starting dose of cabozantinib (20 mg) plus nivolumab for renal cell carcinoma in real-world practice

Tomokazu Sazuka, Sangjon Pae, Yusuke Imamura, Kohei Nagaoka et al.
Japanese Journal of Clinical Oncology
Renal cell carcinoma treatment
article

Efficacy and safety of a reduced starting dose of cabozantinib (20 mg) plus nivolumab for renal cell carcinoma in real-world practice

Tomokazu Sazuka, Sangjon Pae, Yusuke Imamura, Kohei Nagaoka, Yasutaka Yamada, Fusako Yokochi, Keisuke Ando, Kodai Sato, Shinichi Sakamoto, Shinpei Saito, Yuri Watanabe, K. Toma, Y. Onoda
article en

Abstract

A 20-mg starting dose of cabozantinib in C + N therapy can achieve almost the same efficacy as a normal starting dose for patients who are hesitant to start treatment at the normal 40-mg dose.

Japanese Journal of Clinical OncologyVol. 55(12)
Chiba University (JP)
Openalex Percentile: Top 67%
Renal cell carcinoma treatment
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