Alterations of plasma neural-derived extracellular vesicles microRNAs in patients with bipolar disorder

Our findings provide the first evidence of dysregulated plasma miRNAs within neural-derived EVs in BD patients and suggest that neural-derived EVs might be involved in the pathophysiology of BD through related biological pathways, such as neurogenesis and neuroinflammation.

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Publication Details

Journal
Psychological Medicine
Published
2025-01-01
DOI
https://doi.org/10.1017/s0033291725000741
Primary Topic
Extracellular vesicles in disease
Type
article
Field-Weighted Citation Impact
0.00

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article

Alterations of plasma neural-derived extracellular vesicles microRNAs in patients with bipolar disorder

Peiyan Ni, Xueyu Qi, Han Jiang, Wanjun Guo et al.
Psychological Medicine
Extracellular vesicles in disease
article

Alterations of plasma neural-derived extracellular vesicles microRNAs in patients with bipolar disorder

Peiyan Ni, Xueyu Qi, Han Jiang, Wanjun Guo, Bin Ren, Wei Deng, Xueli Yu, Yuqiang Zhou, Tao Li, Yan Xu, Yamin Zhang, Xun Hu, Hua Yu, Jianming Wu
article en

Abstract

Our findings provide the first evidence of dysregulated plasma miRNAs within neural-derived EVs in BD patients and suggest that neural-derived EVs might be involved in the pathophysiology of BD through related biological pathways, such as neurogenesis and neuroinflammation.

Psychological MedicineVol. 55
Shanghai CASB Biotechnology (China) (CN), Interface (United Kingdom) (GB), Zhejiang University (CN)
National Natural Science Foundation of China, Natural Science Foundation of Zhejiang Province
Openalex Percentile: Top 80%
Extracellular vesicles in disease
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Alterations of plasma neural-derived extracellular vesicles microRNAs in patients with bipolar disorder — Peiyan Ni, Xueyu Qi, et al. · Psychological Medicine (2025) | TGRS Research Map | TGRS