Bacillus cereus-derived α-amylase disrupts biofilm formation and quorum sensing in multidrug-resistant Klebsiella pneumoniae

B. cereus-derived α-amylase exhibited potent anti-biofilm, antibacterial, and quorum-quenching activities against K. pneumoniae clinical isolates. These findings highlight its potential as a novel therapeutic agent for managing biofilm-associated infections, either alone or as an adjunct to conventional treatments.

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Publication Details

Journal
BMC Microbiology
Published
2025-08-29
DOI
https://doi.org/10.1186/s12866-025-04301-z
Citations
1
Primary Topic
Bacterial biofilms and quorum sensing
Type
article
Field-Weighted Citation Impact
0.81

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article

Bacillus cereus-derived α-amylase disrupts biofilm formation and quorum sensing in multidrug-resistant Klebsiella pneumoniae

Lamiaa A. Al-Madboly, Amal M. Abo-Kamer, Abd-El-Rahman A. Mustafa
1 citations
BMC Microbiology
Bacterial biofilms and quorum sensing
0.81
article

Bacillus cereus-derived α-amylase disrupts biofilm formation and quorum sensing in multidrug-resistant Klebsiella pneumoniae

Lamiaa A. Al-Madboly, Amal M. Abo-Kamer, Abd-El-Rahman A. Mustafa
article en
1 citations

Abstract

B. cereus-derived α-amylase exhibited potent anti-biofilm, antibacterial, and quorum-quenching activities against K. pneumoniae clinical isolates. These findings highlight its potential as a novel therapeutic agent for managing biofilm-associated infections, either alone or as an adjunct to conventional treatments.

BMC MicrobiologyVol. 25(1)
Tanta University (EG)
Science and Technology Development Fund, Tanta University
Openalex Percentile: Top 24%
Bacterial biofilms and quorum sensing
0.81
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