Refractory “status dyskineticus” in a child with post-herpes simplex virus 1 N-methyl-D-aspartate receptor encephalitis: a case report
This case underscores the crucial role of neurocritical care in managing refractory movement disorders associated with autoimmune encephalitis. Early recognition and immunotherapy escalation are essential to improve outcomes in children with complex, life-threatening neurological conditions. A comprehensive, multidisciplinary approach in the neurocritical care setting is key to achieving recovery and minimizing long-term neurological damage.
Authors
- Alessandro Santagostino Barbone (ORCID: https://orcid.org/0000-0002-8901-9124)
- Maria Margherita Mancardi (ORCID: https://orcid.org/0000-0001-5122-4029)
- Alessia Aiello (ORCID: https://orcid.org/0000-0002-1616-3096)
- Thea Giacomini (ORCID: https://orcid.org/0000-0002-7802-8789)
- Silvia Buratti (ORCID: https://orcid.org/0000-0003-4896-4071)
- Concetta Micalizzi (ORCID: https://orcid.org/0000-0002-7371-1431)
- Camilla Micalizzi (ORCID: https://orcid.org/0000-0002-4645-4572)
- Giacomo Brisca (ORCID: https://orcid.org/0000-0001-7992-0181)
- Elisa De Grandis (ORCID: https://orcid.org/0000-0002-9733-9216)
Institutions
- Istituto Giannina Gaslini (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- University of Genoa (IT)
Publication Details
- Journal
- BMC Neurology
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1186/s12883-025-04346-7
- Primary Topic
- Autoimmune Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministero della Salute