Pathway information on methylation analysis using deep neural network (PROMINENT): An interpretable deep learning method with pathway prior for phenotype prediction using gene-level DNA methylation

PROMINENT represents a significant advancement in leveraging DNA methylation data for phenotype prediction, offering both high accuracy and interpretability within reasonable computational time. This method holds promise for elucidating the epigenetic underpinnings of complex diseases and enhancing the utility of DNA methylation data in biomedical research.