A longitudinal molecular surveillance of genetic heterogeneity of Orientia tsutsugamushi in humans, reservoir animals, and vectors in Puducherry, India
This study provides molecular evidence of the enzootic maintenance and active human transmission of <i>O. tsutsugamushi</i> in Puducherry, with multiple co-circulating serotypes. The first detection of the TA678-like strain in the region suggests the possible introduction of new strains and underscores the need to monitor for strain-specific clinical manifestations in future studies.
Authors
- Aswin Chandrasekaran
- Krishan Kumar Sihag (ORCID: https://orcid.org/0000-0002-1181-0602)
- Anand Kasirajan (ORCID: https://orcid.org/0000-0002-9331-3545)
- Adaikalavan Ramasamy (ORCID: https://orcid.org/0000-0002-7598-2892)
- Nanda Kumar Yellapu (ORCID: https://orcid.org/0000-0002-3095-6375)
- Lakshmy Srinivasan
- Panneer Devaraju (ORCID: https://orcid.org/0000-0003-0638-9590)
- S Srikanth
- Anoop C. Choolayil (ORCID: https://orcid.org/0000-0003-2561-2970)
- Vinod Raveendran
- Waseema Arif
- Mathivanan Ashokkumar
- Asayas Bosco Chandrakumar
- Sivagamy Alias Punitha Thavaraj
Institutions
- Narayana Health (IN)
- Indira Gandhi Medical College and Research Institute (IN)
- Sri Balaji Vidyapeeth University (IN)
- Sri Venkateshwaraa Medical College Hospital and Research Centre (IN)
- Vector Control Research Centre (IN)
- Mahatma Gandhi Medical College and Research Institute (IN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-08-29
- DOI
- https://doi.org/10.3389/fmicb.2025.1634394
- Citations
- 1
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 1.88
Funders
- Indian Council of Medical Research
- Ministry of Health and Family Welfare