Visible-Light-Induced sp<sup>3</sup> C–H Functionalization of Alkyl Amines toward Tetrahydroquinoline Spiro[5.6] Compounds
An efficient and green methodology for the synthesis of tetrahydroquinoline spiro[5.6] compounds by visible-light-induced sp<sup>3</sup> C-H functionalization reactions of alkyl amines has been developed. The advantages of this protocol include inexpensive photocatalysts, high diastereoselectivity, transition-metal-free properties, and wide-scope substrates.
Authors
- Zongkang Wang (ORCID: https://orcid.org/0000-0002-8024-4587)
- Peng He (ORCID: https://orcid.org/0009-0002-2457-5039)
- Yijiao Jiang (ORCID: https://orcid.org/0000-0002-6191-9825)
- Nana Fei (ORCID: https://orcid.org/0000-0002-3531-622X)
- Yanjun Wang (ORCID: https://orcid.org/0009-0001-9975-4376)
- Yanzhong Li (ORCID: https://orcid.org/0000-0002-2898-3075)
- Lingkai Kong
Institutions
- Linyi University (CN)
- East China Normal University (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1021/acs.orglett.5c01130
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China