Case Report: Is there an age cutoff beyond which PFO closure should not be offered?
Enlargement of the aortic root with increasing age may reorientate horizontally the IAS, allowing part of the flow to stream directly toward the PFO, decrease the size and length of IAS, and proportionally increase its mobility, thus uncovering latent or previously trivial RLSs in older hypertensive patients suffering from ESUS.
Authors
- Daniele Andreini (ORCID: https://orcid.org/0000-0002-5996-9209)
- Marco Doldi
- Antonio L. Bartorelli (ORCID: https://orcid.org/0000-0001-9309-2917)
- Francesca Giacomazzi (ORCID: https://orcid.org/0000-0003-4245-5655)
- Eustaquio Onorato (ORCID: https://orcid.org/0000-0002-6750-5682)
- Vincenzo Mallia (ORCID: https://orcid.org/0000-0002-8209-5781)
- Eleonora Melotti (ORCID: https://orcid.org/0000-0003-3604-5094)
- Giovanni Monizzi (ORCID: https://orcid.org/0000-0001-5131-5596)
- Angelo Mastrangelo (ORCID: https://orcid.org/0000-0002-7461-5038)
Institutions
- University of Milan (IT)
- Istituto Clinico Sant'Ambrogio (IT)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2025-08-29
- DOI
- https://doi.org/10.3389/fcvm.2025.1622543
- Primary Topic
- Cardiovascular and Diving-Related Complications
- Type
- article
- Field-Weighted Citation Impact
- 0.00