Global, regional, and national burdens of cirrhosis in childhood and adolescence during 2000 to 2021: an age-period-cohort analysis
During 2000-2021, the burden associated with hepatitis B declined, while the proportion of cirrhosis caused by MAFLD has been steadily increasing. The APC model revealed a consistent global trend of cirrhosis risk, increasing with age but decreasing by period and cohort.
Authors
- Bingcao Wu (ORCID: https://orcid.org/0000-0002-7027-8062)
- Yu‐Chen Fan (ORCID: https://orcid.org/0000-0002-9126-679X)
- Qi An (ORCID: https://orcid.org/0000-0001-7196-5844)
- Xinye Yang
- Jie-Ru Yang
- Yao Yao (ORCID: https://orcid.org/0000-0002-6723-6152)
- Yuxin Tian (ORCID: https://orcid.org/0000-0003-2066-9599)
- Xinjing Yang
- Jing Zuo
Institutions
- Shandong University (CN)
- Qilu Hospital of Shandong University (CN)
Publication Details
- Journal
- Frontiers in Public Health
- Published
- 2025-08-29
- DOI
- https://doi.org/10.3389/fpubh.2025.1638207
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shandong University
- National Natural Science Foundation of China