Zebrafish-based assessment of luteolin’s potential in modulating seizure responses
These findings provide initial evidence that luteolin, in both raw and micronized forms, has antiseizure properties in developing zebrafish. Further research is needed to uncover the pharmacokinetic profile and mechanisms involved.
Authors
- Mariana Appel Hort (ORCID: https://orcid.org/0000-0001-5877-3506)
- Gean Pablo S. Aguiar (ORCID: https://orcid.org/0000-0002-3501-8054)
- Anna Maria Siebel (ORCID: https://orcid.org/0000-0002-7896-1456)
- Samara Cristina Mazon (ORCID: https://orcid.org/0000-0002-9197-2811)
- Aline E. dos Santos (ORCID: https://orcid.org/0000-0003-0254-0484)
- Liz Girardi Müller (ORCID: https://orcid.org/0000-0002-4479-889X)
- Marcelo Lanza (ORCID: https://orcid.org/0000-0002-5133-7397)
- Sabrina Ester Schneider (ORCID: https://orcid.org/0000-0001-8701-391X)
- J. Vladimir Oliveira (ORCID: https://orcid.org/0000-0002-6196-3498)
- Ângelo Piato (ORCID: https://orcid.org/0000-0001-5109-7306)
- Cássia Alves Lima‐Rezende (ORCID: https://orcid.org/0000-0001-7615-7635)
- Jefferson Pedroso
Institutions
- Universidade Federal do Rio Grande (BR)
- Universidade Federal do Rio Grande do Sul (BR)
- Community University of Chapecó Region - Unochapecó (BR)
- Universidade Federal de Santa Catarina (BR)
- Instituto de Biologia Experimental e Tecnológica (PT)
- Universidade Federal do Paraná (BR)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-08-29
- DOI
- https://doi.org/10.3389/fphar.2025.1656301
- Primary Topic
- Zebrafish Biomedical Research Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universidade Comunitária da Região de Chapecó
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação de Amparo à Pesquisa e Inovação do Estado de Santa Catarina