Multicenter epidemiological distribution, pathogens, and drug-resistance characteristics of chronic osteomyelitis in Central China
Chronic osteomyelitis predominantly affects middle-aged and older adults, males, and those with tibial injuries from traffic accidents requiring special attention. <i>Staphylococcus aureus</i> was associated with the highest risk of infection. Empirical early-phase medication should be followed by targeted antibiotic therapy based on bacterial sensitivity and resistance. Patients with prolonged hospitalization, diabetes, or a smoking history require special attention. Notably, strengthening health education and postoperative care in these patients can reduce the risk of chronic osteomyelitis.
Authors
- Rihong Zhang (ORCID: https://orcid.org/0000-0002-2461-9233)
- Gang Jin (ORCID: https://orcid.org/0000-0001-6713-1185)
- Xiaoqing Liu (ORCID: https://orcid.org/0000-0002-4034-5156)
- Le Zhang (ORCID: https://orcid.org/0000-0002-6930-8674)
- Dong Wang (ORCID: https://orcid.org/0000-0002-5788-245X)
- Yonghong Zhang (ORCID: https://orcid.org/0000-0002-7305-9295)
- Yan Li (ORCID: https://orcid.org/0000-0002-7619-2809)
- Zemin Liu (ORCID: https://orcid.org/0000-0002-2261-2812)
Institutions
- Changzhi University (CN)
- Shanxi Medical University (CN)
- Xian Center for Disease Control and Prevention (CN)
- Second Hospital of Shanxi Medical University (CN)
Publication Details
- Journal
- Frontiers in Public Health
- Published
- 2025-08-29
- DOI
- https://doi.org/10.3389/fpubh.2025.1654861
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China