Intrathecal silymarin administration improves recovery after compression spinal cord injury: evidence for neuroprotection, antioxidant, and anti-inflammatory action
Generally, intrathecal injection of SIL after SCI provides neuroprotective, anti-inflammatory, and antioxidant effects leading to pain reduction and improved motor function in rats.
Authors
- Sajad Fakhri
- Javier Echeverría (ORCID: https://orcid.org/0000-0002-1688-968X)
- Amir Kiani (ORCID: https://orcid.org/0000-0002-7802-2117)
- Khodabakhsh Rashidi (ORCID: https://orcid.org/0000-0002-8144-074X)
- Fatemeh Abbaszadeh (ORCID: https://orcid.org/0000-0002-1374-3554)
- Omar Bahmani
Institutions
- Universidad de Santiago de Chile (CL)
- Kermanshah University of Medical Sciences (IR)
- Shahid Beheshti University of Medical Sciences (IR)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-08-29
- DOI
- https://doi.org/10.3389/fphar.2025.1592682
- Citations
- 2
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.33
Funders
- Kermanshah University of Medical Sciences