High-glucose diets differentially modulate phosphatidylcholine metabolism and fecundity in Caenorhabditis elegans
We demonstrate that dietary cues under high-glucose conditions modulate a genetic network linking lipid homeostasis and signaling pathways, ultimately determining fecundity outcomes in <i>C. elegans</i>.
Authors
- Xiaofei Bai (ORCID: https://orcid.org/0000-0001-8179-8162)
- Yet‐Ran Chen (ORCID: https://orcid.org/0000-0002-2409-6655)
- Yi‐Chun Wu (ORCID: https://orcid.org/0000-0002-8621-4098)
- Chao-Wen Wang (ORCID: https://orcid.org/0000-0002-4073-299X)
- You-Liang Cheng (ORCID: https://orcid.org/0000-0003-1836-5836)
- Rey‐Huei Chen (ORCID: https://orcid.org/0000-0002-6006-2137)
- Yu‐Ching Wu (ORCID: https://orcid.org/0000-0002-6989-6525)
- Pei-Chen Chiu
- John H. Law
- Sophia Monsalve
- Ricardo Roure
Institutions
- National Taiwan University (TW)
- University of Florida (US)
- Institute of Plant and Microbial Biology, Academia Sinica (TW)
- Institute of Molecular Biology, Academia Sinica (TW)
- Agricultural Biotechnology Research Center, Academia Sinica (TW)
- National Cheng Kung University (TW)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-08-29
- DOI
- https://doi.org/10.3389/fcell.2025.1622695
- Primary Topic
- Genetics, Aging, and Longevity in Model Organisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00