Systemic inflammation versus clinical demographics: patient age surpasses the platelet-to-lymphocyte ratio in differentiating secondary trigeminal neuralgia
While this study identified PLR as a potential auxiliary biomarker, its most crucial finding is that the simple demographic feature of patient age is the primary and more powerful discriminator for differentiating STN-M from STN-E. This highlights that while novel biomarkers should be explored, the foundational importance of basic clinical parameters must not be overlooked in the pursuit of diagnostic precision.
Authors
- Ruen Liu (ORCID: https://orcid.org/0000-0002-2405-5597)
- Shijun Peng
- Xin Chang (ORCID: https://orcid.org/0009-0003-2863-6019)
- Qingpei Hao (ORCID: https://orcid.org/0000-0002-2234-976X)
- Yuepeng Wang
- Tao Wang (ORCID: https://orcid.org/0000-0003-1225-0173)
- Zi-Hao Zhang (ORCID: https://orcid.org/0009-0001-0191-1725)
- Jun Ouyang (ORCID: https://orcid.org/0009-0004-5273-7845)
Institutions
- Hebei Medical University (CN)
- Peking University (CN)
- Peking University People's Hospital (CN)
- University of South China (CN)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2025-08-29
- DOI
- https://doi.org/10.3389/fnagi.2025.1658854
- Primary Topic
- Trigeminal Neuralgia and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Beijing Municipal Health Commission
- Peking University
- Peking University People's Hospital