Case Report: X-linked agammaglobulinemia with progressive neurodegeneration from immunological to neurological implications
Severe progressive neurodegeneration in XLA is rare. With this case we would like to discuss the difficulties in diagnosing infection in patients with XLA and the role of autoimmune mechanisms in the development of neurodegeneration.
Authors
- Xiaoyi Chen (ORCID: https://orcid.org/0000-0002-4428-4418)
- Yiran Zhao (ORCID: https://orcid.org/0000-0001-6543-561X)
- Huawei Mao (ORCID: https://orcid.org/0009-0003-4035-3775)
- Yurong Piao
- Yuan Wang (ORCID: https://orcid.org/0000-0002-7355-9505)
- Yanli Ma (ORCID: https://orcid.org/0000-0001-5039-5424)
- Hao Gu (ORCID: https://orcid.org/0000-0002-8623-5649)
- Jie Deng
Institutions
- Zhengzhou Children's Hospital (CN)
- Beijing Children’s Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-08-29
- DOI
- https://doi.org/10.3389/fimmu.2025.1611748
- Primary Topic
- Immunodeficiency and Autoimmune Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00