A multi-centre observational cohort study on pharmacogenomic predictors of rosuvastatin discontinuation in a multiethnic population
Minor allele carriers are at higher risk of discontinuation due to adverse effects. Genetic testing for <i>ABCG2</i> may support personalized rosuvastatin therapy and improve adherence.
Authors
- Zeina N. Al-Mahayri (ORCID: https://orcid.org/0000-0002-4673-6692)
- Mais N. Alqasrawi
- George P. Patrinos (ORCID: https://orcid.org/0000-0002-0519-7776)
- Sahar M. Altoum (ORCID: https://orcid.org/0000-0002-7944-9905)
- Dana Hamza
- Mohammad M. AlAhmad (ORCID: https://orcid.org/0000-0003-0344-4056)
- Juma Alkaabi (ORCID: https://orcid.org/0000-0003-2477-0408)
- Virendra Misra
- Salahdein Aburuz (ORCID: https://orcid.org/0000-0002-2478-3914)
- Gohar Jamil (ORCID: https://orcid.org/0000-0002-6614-6286)
- Fatma Al‐Maskari (ORCID: https://orcid.org/0000-0001-6598-4942)
- Bassam R. Ali (ORCID: https://orcid.org/0000-0003-1306-6618)
- Faiz Al-Bakshy
- Areej S. Albawa’neh (ORCID: https://orcid.org/0000-0002-8782-308X)
- Lubna Q. Khasawneh (ORCID: https://orcid.org/0000-0001-6090-5969)
- Husam Ouda
- Lilas Dabaghie
- Khuzama AlAhamad
Institutions
- Abu Dhabi University (AE)
- Al Ain University (AE)
- University of Patras (GR)
- United Arab Emirates University (AE)
- Emirates Foundation (AE)
- Tawam Hospital (AE)
- Al Ain Hospital (AE)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-08-29
- DOI
- https://doi.org/10.3389/fphar.2025.1656520
- Citations
- 1
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- Ministry of Higher Education and Scientific Research
- United Arab Emirates University