Efficacy and safety of dolutegravir plus lamivudine for patients with late presentation of HIV-1 infection: a retrospective real-world cohort study in Southwest China

DTG + 3TC demonstrated high virologic efficacy and good tolerability in patients with late presentation. However, the regimen may be associated with an increase in lipid levels and weight, highlighting the need for regular monitoring.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-08-29
DOI
https://doi.org/10.3389/fmed.2025.1630960
Primary Topic
HIV/AIDS drug development and treatment
Type
article
Field-Weighted Citation Impact
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article

Efficacy and safety of dolutegravir plus lamivudine for patients with late presentation of HIV-1 infection: a retrospective real-world cohort study in Southwest China

Xiaoxin Xie, Peng Jiao, Hai Long, Lin Gan et al.
Frontiers in Medicine
HIV/AIDS drug development and treatment
article

Efficacy and safety of dolutegravir plus lamivudine for patients with late presentation of HIV-1 infection: a retrospective real-world cohort study in Southwest China

Xiaoxin Xie, Peng Jiao, Hai Long, Lin Gan, Yanhua Fu, Jun Li, Shujing Ma, Xiaoyan Yang, Mei-Hua Wu, Qing Wang
article en

Abstract

DTG + 3TC demonstrated high virologic efficacy and good tolerability in patients with late presentation. However, the regimen may be associated with an increase in lipid levels and weight, highlighting the need for regular monitoring.

Frontiers in MedicineVol. 12
Guiyang Medical University (CN), Shanghai Public Health Clinical Center (CN)
Openalex Percentile: Top 73%
HIV/AIDS drug development and treatment
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